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Selected Publications
Molecular Neuro-Oncology Laboratory
David N. Louis, M.D.

[NIH NLM PubMed Search][NIH NLM PubMed Search] National Libraries of Medicine
National Institutes of Health
PubMed Search

Louis Publications
Louis Pubs 2005
Louis Pubs 2004
Louis Pubs 2003
Louis Pubs 2002
Louis Pubs 2001
Louis Pubs 2000
Louis Pubs 1999

"NOTICE: The PubMed data are for personal use only. Users are responsible for complying with all copyright and licensing restrictions associated with data."
Brecher K, et al.           [See Related Articles]
Case report of unusual leukoencephalopathy preceding primary CNS lymphoma.
J Neurol Neurosurg Psychiatry. 1998 Dec;65(6):917-20.
[MEDLINE record in process]
PMID: 9854972; UI: 99070614.
Cairncross JG, et al.           [See Related Articles]
Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas.
J Natl Cancer Inst. 1998 Oct 7;90(19):1473-9.
PMID: 9776413; UI: 98447308.
Herrlinger U, et al.           [See Related Articles]
Pre-existing herpes simplex virus 1 (HSV-1) immunity decreases, but does not abolish, gene transfer to experimental brain tumors by a HSV-1 vector.
Gene Ther. 1998 Jun;5(6):809-19.
PMID: 9747461; UI: 98419598.
Nielsen GP, et al.           [See Related Articles]
CDKN2A gene deletions and loss of p16 expression occur in osteosarcomas that lack RB alterations.
Am J Pathol. 1998 Jul;153(1):159-63.
PMID: 9665476; UI: 98328413.
Ohh M, et al.           [See Related Articles]
The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix.
Mol Cell. 1998 Jun;1(7):959-68.
PMID: 9651579; UI: 98315379.
Duerr EM, et al.           [See Related Articles]
PTEN mutations in gliomas and glioneuronal tumors.
Oncogene. 1998 Apr 30;16(17):2259-64.
PMID: 9619835; UI: 98281134.
Husain N, et al.           [See Related Articles]
Co-expression of Fas and Fas ligand in malignant glial tumors and cell lines.
Acta Neuropathol (Berl). 1998 Mar;95(3):287-90.
PMID: 9542594; UI: 98203721.
Burns KL, et al.           [See Related Articles]
Molecular genetic correlates of p16, cdk4, and pRb immunohistochemistry in glioblastomas.
J Neuropathol Exp Neurol. 1998 Feb;57(2):122-30.
PMID: 9600204; UI: 98260831.
Cheng LL, et al.           [See Related Articles]
Correlation of high-resolution magic angle spinning proton magnetic resonance spectroscopy with histopathology of intact human brain tumor specimens.
Cancer Res. 1998 May 1;58(9):1825-32.
PMID: 9581820; UI: 98240976.
Cobbers JM, et al.           [See Related Articles]
Frequent inactivation of CDKN2A and rare mutation of TP53 in PCNSL.
Brain Pathol. 1998 Apr;8(2):263-76.
PMID: 9546285; UI: 98206361.
Bakshi R, et al.           [See Related Articles]
Magnetic resonance imaging features of solitary inflammatory brain masses.
J Neuroimaging. 1998 Jan;8(1):8-14.
PMID: 9442584; UI: 98104714.
Chung DC, et al.           [See Related Articles]
Analysis of the retinoblastoma tumour suppressor gene in pancreatic endocrine tumours.
Clin Endocrinol (Oxf). 1997 Nov;47(5):523-8.
PMID: 9425391; UI: 98086528.
Herrlinger U, et al.           [See Related Articles]
Vaccination for experimental gliomas using GM-CSF-transduced glioma cells.
Cancer Gene Ther. 1997 Nov-Dec;4(6):345-52.
PMID: 9408604; UI: 98072902.
Stemmer-Rachamimov AO, et al.           [See Related Articles]
Universal absence of merlin, but not other ERM family members, in schwannomas.
Am J Pathol. 1997 Dec;151(6):1649-54.
PMID: 9403715; UI: 98065973.
Mason W, et al.           [See Related Articles]
Chemosensitive gliomas in adults: which ones and why?
J Clin Oncol. 1997 Dec;15(12):3423-6. Review. No abstract available.
PMID: 9396392; UI: 98057065.
Maintz D, et al.           [See Related Articles]
Molecular genetic evidence for subtypes of oligoastrocytomas.
J Neuropathol Exp Neurol. 1997 Oct;56(10):1098-104.
PMID: 9329453; UI: 97470036.
Ueki K, et al.           [See Related Articles]
Chromosomal localization to 19q13.3, partial genomic structure and 5' cDNA sequence of the human symplekin gene.
Somat Cell Mol Genet. 1997 May;23(3):229-31.
PMID: 9330635; UI: 97471694.
Jones RM, et al.           [See Related Articles]
Assignment of the human gene encoding eukaryotic initiation factor 4E (EIF4E) to the region q21-25 on chromosome 4.
Somat Cell Mol Genet. 1997 May;23(3):221-3.
PMID: 9330633; UI: 97471692.
Meyer-Puttlitz B, et al.           [See Related Articles]
Molecular genetic analysis of giant cell glioblastomas.
Am J Pathol. 1997 Sep;151(3):853-7.
PMID: 9284834; UI: 97430727.
Hsu DW, et al.           [See Related Articles]
Use of MIB-1 (Ki-67) immunoreactivity in differentiating grade II and grade III gliomas.
J Neuropathol Exp Neurol. 1997 Aug;56(8):857-65.
PMID: 9258255; UI: 97402877.
Chung DC, et al.           [See Related Articles]
A novel pancreatic endocrine tumor suppressor gene locus on chromosome 3p with clinical prognostic implications.
J Clin Invest. 1997 Jul 15;100(2):404-10.
PMID: 9218518; UI: 97364808.
Ono Y, et al.           [See Related Articles]
Accumulation of wild-type p53 in astrocytomas is associated with increased p21 expression.
Acta Neuropathol (Berl). 1997 Jul;94(1):21-7.
PMID: 9224526; UI: 97367823.
Hayashi Y, et al.           [See Related Articles]
Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme.
Brain Pathol. 1997 Jul;7(3):871-5.
PMID: 9217972; UI: 97361009.
Platten M, et al.           [See Related Articles]
A novel splice site associated polymorphism in the tuberous sclerosis 2 (TSC2) gene may predispose to the development of sporadic gangliogliomas.
J Neuropathol Exp Neurol. 1997 Jul;56(7):806-10.
PMID: 9210877; UI: 97354650.
Stemmer-Rachamimov AO, et al.           [See Related Articles]
Expression of NF2-encoded merlin and related ERM family proteins in the human central nervous system.
J Neuropathol Exp Neurol. 1997 Jun;56(6):735-42.
PMID: 9184664; UI: 97328106.
Stemmer-Rachamimov AO, et al.           [See Related Articles]
Histopathologic and immunohistochemical prognostic factors in malignant gliomas.
Curr Opin Oncol. 1997 May;9(3):230-4. Review.
PMID: 9229144; UI: 97373091.
Stemmer-Rachamimov AO, et al.           [See Related Articles]
Meningioangiomatosis is associated with neurofibromatosis 2 but not with somatic alterations of the NF2 gene.
J Neuropathol Exp Neurol. 1997 May;56(5):485-9. Review.
PMID: 9143261; UI: 97288283.
Louis DN.           [See Related Articles]
A molecular genetic model of astrocytoma histopathology.
Brain Pathol. 1997 Apr;7(2):755-64. Review.
PMID: 9161727; UI: 97305469.
Listernick R, et al.           [See Related Articles]
Optic pathway gliomas in children with neurofibromatosis 1: consensus statement from the NF1 Optic Pathway Glioma Task Force.
Ann Neurol. 1997 Feb;41(2):143-9. No abstract available.
PMID: 9029062; UI: 97180844.

Representative Publications

von Deimling A, von Ammon K, Schoenfeld DA, Wiestler OD, Seizinger BR, Louis DN. Subsets of glioblastoma multiforme defined by molecular genetic analysis. Brain Pathol 3:19-26, 1993.

Henson JW, Schnitker BL, Correa K, von Deimling A, Fassbinder F, Xu H-J, Benedict WF, Yandell DW, Louis DN. The retinoblastoma gene is involved in the malignant progression of astrocytomas. Ann Neurol 36:714-721, 1994.

Rubio M-P, Correa KM, Ueki K, Mohrenweiser HW, Gusella JF, von Deimling A, Louis DN. The putative glioma tumor suppressor gene on chromosome 19q maps between APOC2 and HRC. Cancer Res 54:4760-4763, 1994.

Louis DN. The p53 gene and protein in human brain tumors. J Neuropathol Exp Neurol 53:11-21, 1994.

Louis DN, Gusella JF. A tiger behind many doors: multiple pathways to malignant glioma. Trends in Genetics 11:412-415, 1995.

Yong WH, Ueki K, Chou D, Reeves SA, von Deimling A, Gusella JF, Mohrenweiser HW, Buckler AJ, Louis DN. Cloning of a highly conserved human protein serine-threonine phosphatase from the glioma candidate region on chromosome 19q13.3. Genomics 29:533-536, 1995.

Ueki K, Ono Y, Henson JW, Efird JT, von Deimling A, Louis DN. CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated. Cancer Res 56:150-153, 1996.

Ono Y, Tamiya T, Ichikawa T, Kunishio K, Matsumoto K, Furuta T, Ohmoto T, Ueki K, Louis DN. Malignant astrocytomas with homozygous CDKN2/p16 gene deletions have higher Ki-67 proliferation indices. J Neuropathol Exp Neurol 55:1026-1031, 1996.

Rosenberg JE, Lisle DK, Burwick JA, Ueki K, von Deimling A, Mohrenweiser HW, Louis DN. Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval. Oncogene 13:2483-2485, 1996.

Ueki K, Ramaswamy S, Billings SJ, Mohrenweiser HW, Louis DN. ANOVA, a putative astrocytic RNA-binding protein gene that maps to chromosome 19q13.3. Neurogenetics 1:31-36, 1997.

Stemmer-Rachamimov AO, Gonzalez-Agosti C, Xu L, Burwick JA, Beauchamp R, Pinney D, Louis DN, Ramesh V. Expression of NF2-encoded merlin and related ERM family proteins in the human central nervous system. J Neuropathol Exp Neurol 56:735-742, 1997.

Louis DN, Cavenee WK. Molecular biology of central nervous system tumors. In: Cancer: Principles and Practice of Oncology. DeVita VT, Hellman S, Rosenberg SA (eds.). Philadelphia: Lippincott-Raven, 1997.

Louis DN. A molecular genetic model of astrocytoma histopathology. Brain Pathol 7:755-764, 1997.

Mason W, Louis DN, Cairncross JG. Chemosensitive gliomas: which ones and why? J Clin Oncol 15:3423-3426, 1997.

Stemmer-Rachamimov AO, Horgan M, Taratuto AL, Munoz DG, Smith TW, Frosch MP, Louis DN. Meningioangiomatosis is associated with neurofibromatosis 2 but not with somatic alterations of the NF2 gene. J Neuropathol Exp Neurol 56:485-489, 1997.

Stemmer-Rachamimov AO, Xu L, Gonzalez-Agosti C, Burwick J, Pinney D, Beauchamp R, Jacoby LB, Gusella JF, Ramesh V, Louis DN. Universal absence of merlin, but not other ERM family members, in schwannomas. Am J Pathol 152:1649-1654, 1997.

Burns KL, Ueki K, Jhung SL, Koh J, Louis DN. Molecular genetic correlates of p16, cdk4 and pRb immunohistochemistry in glioblastomas. J Neuropathol Exp Neurol 57:122-130, 1998.

Cairncross JG, Ueki K, Zlatescu MC, Lisle DK, Finkelstein DM, Hammond RR, Silver JS, Stark PC, Macdonald DR, Ino Y, Ramsay DA, Louis DN. Specific chromosomal losses predict chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas. J Natl Canc Inst 90:1473-1479, 1998.

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