Bob S. Carter, MD, Ph.D. 
Assistant Professor of Neurosurgery

• Aneurysm and AVM Center
• Carotid endarterectomy to prevent stroke (brain attack) and transient ischemic attack (tia).

• Brain AVM and Aneurysm Center
• Neurooncology
• Brain Tumor Center
• Interventional Neuroradiology Center

Selected Publications:

• Carter BS, Boehm T, Folkman J, and Mulligan RC.  A Novel Secreted form of the Angiogenesis Inhibitor Endostatin Inhibits the Growth of Human Glioma Xenografts.  Preuss Award, Joint Section of Neuroncology, Podium Presentation, Congress of Neurologic Surgeons, Seattle WA 1998
• Carter BS, Ghogawala Z, Niederman T, and Mulligan RC.  Specific Killing of EGFRvIII expressing Tumor Cells by Genetically Engineered Cytotoxic T-Lymphocytes.  . Podium Presentation.  Congress of Neurologic Surgeons.  Seattle WA 1998
• Carter BS, Ogilvy CS, Putnam C and Ojemann R. The Case for Selective Use of Extracranial-Intracranial Bypass as an Adjunct to Therapeutic Carotid Artery Occlusion. Clinical Neurosurgery 1998 (In Press)
• Carter BS, Buckley D, Ferraro R, Rordorf G, and Ogilvy CS. Self-Reported Long Term Outcome after Subarachnoid Hemorrhage:   Physical, Psychiatric, and Social Recovery in Hunt and Hess Grades 1-3 Patients (submitted)
• Ogilvy CS and Carter BS. A proposed comprehensive grading system to predict outcome for surgical management of intracranial aneurysms. Neurosurgery.  42: 959-968 (1998).
• Bova GS, Partin SD, Isaacs S, Carter BS, Beaty TL, Isaacs WB and Walsh PC, Biological Aggressiveness of Hereditary Prostate Cancer:  Long Term Evaluation Following Radical Prostatectomy  J. Urology 160:  660-665 (1998)
• Carter BS, Ogilvy CS, Rosas, H.D., Buonanno F. Long term Outcome after Hemicraniectomy for Massive Non-dominant Hemispheric Infarction. Neurosurgery 40:  1168-1175, (1997)
• Ogilvy CS, Carter BS, Kaplan S, Rich C, Crowell RM.  Factors affecting stroke incidence during aneurysm surgery with temporary vessel occlusion in patients protected by hypertension, hypothermia, and intravenous mannitol. J Neurosurg 84, 785-791 (1996)
• Brooks JD, Bova GS, Ewing CM, Piantadosi S, Carter BS, Robinson JC, Epstein JI, Isaacs WB.  An uncertain role for p53 gene alterations in human prostate cancers.  Cancer Research 56:3814-3822. (1996)
• Bova GS, Carter BS, Bussemakers MJG, Emi M, Fujiwara Y, Kyprianou N, Jacobs SC, Robinson JC, Epstein JI, Walsh PC, and Isaacs WB. (1993)   Homozygous deletion and frequent allelic loss of chromosome 8p22 loci in human prostate cancer.  Cancer Research 53:3869-3873.
• Carter BS, Bova GS, Steinberg GD, Beaty TH, Isaacs WB, and Walsh PC.  Hereditary Prostate Cancer:  Clinical and Epidemiologic Features (1993) Journal of Urology 150:797-802.
• Umbas R, Schalken JA, Aalders TW, Carter BS, Karthaus HF, Schaafsma HE, Debryne FM, and Isaacs WB.  Decreased expression of e-cadherin in high grade prostatic carcinomas. (1992)  Cancer Research 52:5104-9.
• Carter BS, Beaty TH, Steinberg GD, Childs B and Walsh PC.  Mendelian Inheritance of Early Onset Familial Prostate Cancer. (1992) Proc Natl Acad Sci (USA)  89: 3367-3371.
• Newmark  JR, Hardy DO, Tonb DC, Carter BS, Epstein JI, Isaacs WB, Brown TR, and Barrack ER.  Androgen receptor mutation in human prostate cancer.  (1992)  Proc Natl Acad Sci (USA) 89:6319-23.
• Isaacs WB, Carter BS, and Ewing CM.  Wild type p53 Suppresses Growth of Human Prostate Cancer Cells containing Mutant p53 Alleles. (1991)  Cancer Research, 51:4716-20.
• Quinlan DM, Epstein JI, Carter BS, and Walsh PC.  Sexual Function following Radical Prostatectomy:  Influence of Preservation of Neurovascular Bundles (1991) Journal of Urology 145:998-1002.
• Carter BS, Ewing CM, Ward WS, Treiger BT, Aalders TW, Schalken JA, Epstein, JI, and Isaacs WB Allelic Loss On Chromosomes 10q and 16q in Human Prostate Cancer. (1990) Proc. Natl. Acad. Sci. 87:8751-8755.
• Steinberg GD, Carter BS, Beaty TH, Childs B, and Walsh PC. Family History and the Risk of Prostate Cancer. (1990) Prostate 17:337-347.
• Carter BS, Epstein JI, and Isaacs WB ras Gene Mutations in Human Prostate Cancer. (1990) Cancer Res. 50:6830-6832
• Carter BS, Carter HB, Isaacs JT. Epidemiologic Evidence Regarding Predisposing Factors to Prostate Cancer (1990) Prostate 16:187-197.
• Carter BS, Isaacs JT.  Predisposing Factors to Prostate Cancer.  Reviews on Endocrine Related Cancer (1990) 34:13-18.

Bibliography (Chapters):

• Carter BS, Zervas NT, Chiocca EA.  Neurogenetic Surgery:  Current Limitations and Future Promise of Gene and Cell Based Therapies.  Clinical Neurosurgery (1998, In Press)
• Yu JS, Carter BS, Harsh G, Gene Therapy for Cerebral Metastasis, in Advanced Techniques in Central Nervous System Metastases, Ed: Robert J. Maciunas, MD.  AANS Publications 1998
• Carter BS, Buckley Dierdre, Ferraro R, and Ogilvy CS  Neuroviews:  Social, Legal, and Ethical Implications of Subarachnoid Hemorrhage.  UpJohn Co. 1997
• Carter BS, Ogilvy CS.  Editorial Comment on “Expression of Angiogenic Factors and Structural Proteins in Central Nervous System Vascular Malformations.  Neurosurgery 38:915.  1996.
• Carter BS and Harsh G. Diagnosis of Suspected Intracranial Metastases:  Role of Direct Tissue Examination.  In: Cerebral Metastases. (Harsh G, Ed.),  Neurosurgery Clinics of North America 7:425-433. 1996
• Carter BS and Ogilvy CS.  Emergency managment of Stroke with Hemicraniectomy.  Cerebrovascular News. Mass General Hospital. 1995.
• Carter BS, Steinberg GD, Beaty TH, Childs B, Walsh PC.  Familial Risk Factors for Prostate Cancer. In:  Cancer Surveys on Prostate Cancer - Cellular and Molecular Mechanisms in Diagnosis and Treatment (Franks, L.M. Ed.), 1992.
• Isaacs WB and Carter BS  Genetic Changes Associated with Prostate Cancer in Humans.  In:  Cancer Surveys on Prostate Cancer - Cellular and Molecular Mechanisms in Diagnosis and Treatment (Franks, L.M. Ed.), 1992.
• Isaacs WB, Morton RA, Carter BS, Ewing CM, Chevrier M, and Epstein JI. Genomic Alterations in Prostatic Cancer. In: Molecular and Cellular Biology of Prostate Cancer. (Coffey, D.S., Smith, R.G., Tindall, D.J., and Karr, J.P., Eds.), Plenum Press, New York, 1992.

Neurosurgery Clinical Units MGH Neurosurgical Service Spine Tumor Center at MGH Brain Tumor Center at MGH Research at MGH Neurosurgery Neuroscience Care Units at MGH Residents at Neurosurgery